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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 37087Erstellt: 24. Oktober 2026

Hydrochloric Acid → 9-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl)adenine hydrochloride

https://huagongshe.com/de/reaction/37087

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktHydrochloric AcidHCID 313—
EduktIsopropanolHCID 3776—
Edukt2'-Fluoro-2'-deoxyadenosineHCID 100253—
LösungsmittelMethanolHCID 887—
LösungsmittelWaterHCID 962—
Produkt9-(2-Deoxy-2-fluoro-beta-D-ribofuranosyl)adenine hydrochlorideHCID 67740756—

Reaktionsschritte

To a solution of 9-(2-deoxy-2-fluoro-β-D-ribofuranosyl)adenine (500 mg. 1.86 mmol) in MeOH (40 ml) and water (10 ml) was added a solution of isopropanol (15 ml) previously saturated with HCl gas. The solution was evaporated under vacuum at room temperature, and triturated with EtOH (25 ml) to afford the title compound as a white solid.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05420115
Quelldatensatzuspto-grants-1995_05
ORD IDord-6f3bdcf96f5c441380f7fe1672130045
Quellennotizuspto-grants-1995_05