Thionyl Chloride → N-Octyl 4-Chlorobenzimidoyl Chloride

HRID 370916Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 370916
[CH2:1]([NH:9][C:10](=O)[C:11]1[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].S(Cl)([Cl:21])=O>>[CH2:1]([N:9]=[C:10]([Cl:21])[C:11]1[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 17219574-chloro-N-octylbenzamide

Produkt 1

HCID 13477601N-Octyl 4-Chlorobenzimidoyl ChlorideAusbeute 77 %

Versuchsvorschrift

N-Octyl 4-chlorobenzamide (17.2 g, 64.2 mmole) and thionyl chloride (42.59 g, 358 mmole) were stirred and heated at reflux for one hour. The product was isolated by fractional distillation at reduced pressure (b.p. 70°-90° C. at 15 mm Hg) to yield 14.0 g (77%) of impure title compound.

Aufarbeitung

  1. temperatureheated
  2. temperatureat reflux for one hour
  3. customThe product was isolated by fractional distillation at reduced pressure (b.p. 70°-90° C. at 15 mm Hg)

Quellen und Nachweise

ORD-Eintrag
ord-d8717f55b0014481a130076770b05e2f
Quelldatensatz
uspto-grants-1985_07
Patentnummer
US04528382

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