Tetrahydrofuran → 1-Diallylcarbamoyl-3-n-butylsulphinyl-1,2,4-triazole

HRID 371573Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 371573
[CH2:1]([S:5]([C:7]1[N:11]=[CH:10][NH:9][N:8]=1)=[O:6])[CH2:2][CH2:3][CH3:4].[CH2:12]([N:15]([CH2:19][CH:20]=[CH2:21])[C:16](Cl)=[O:17])[CH:13]=[CH2:14].O1CCCC1>C(N(CC)CC)C>[CH2:12]([N:15]([CH2:19][CH:20]=[CH2:21])[C:16]([N:9]1[CH:10]=[N:11][C:7]([S:5]([CH2:1][CH2:2][CH2:3][CH3:4])=[O:6])=[N:8]1)=[O:17])[CH:13]=[CH2:14]

Komponenten

5

Edukt 3

HCID 8028TetrahydrofuranHCID 3449313Diallylcarbamyl chlorideHCID 1784555543-Butylsulphinyl-1,2,4-triazole

Produkt 1

HCID 203551101-Diallylcarbamoyl-3-n-butylsulphinyl-1,2,4-triazole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8471TriethylamineLösungsmittel

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

A mixture of 5.2 g. 3-butylsulphinyl-1,2,4-triazole, 6.0 g. diallylcarbamoyl chloride, 25 ml. dry tetrahydrofuran and 7.5 ml. dry triethylamine was refluxed under anhydrous conditions for 2 hours. The reaction mixture was filtered to remove triethylamine hydrochloride and the filtrate distilled under reduced pressure to remove solvent. Finally the residue was maintained at 100° C./0.5 mm. for 30 minutes in order to remove all traces of volatile material from the product. The product, 1-diallylcarbamoyl-3-n-butylsulphinyl-1,2,4-triazole, was obtained as an oil, nD26 1.5277. Elemental analysis satisfactory.

Aufarbeitung

  1. additionA mixture of 5.2 g
  2. filtrationThe reaction mixture was filtered
  3. customto remove triethylamine hydrochloride
  4. distillationthe filtrate distilled under reduced pressure
  5. customto remove solvent
  6. customfor 30 minutes in order to remove all traces of volatile material from the product

Quellen und Nachweise

ORD-Eintrag
ord-d768bd286f2e40d1963ca1e7638937cb
Quelldatensatz
uspto-grants-1978_05
Patentnummer
US04087269

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