Dioctadecylamine → ethyl 4-Dioctadecylaminobutyrate

HRID 371788Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 371788
[CH2:1]([NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].Br[CH2:39][CH2:40][CH2:41][C:42]([O:44][CH2:45][CH3:46])=[O:43]>C1(C)C=CC=CC=1>[CH2:20]([N:19]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[CH2:39][CH2:40][CH2:41][C:42]([O:44][CH2:45][CH3:46])=[O:43])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH3:37]

Komponenten

4

Edukt 2

HCID 66989DioctadecylamineHCID 76300Ethyl 4-bromobutyrate

Produkt 1

HCID 20433003ethyl 4-DioctadecylaminobutyrateAusbeute 58,2 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

A solution of dioctadecylamine (5.2 g., 0.01 mole), ethyl 4-bromobutyrate (1.95 g., 0.01 mole) and toluene (50 ml.) is heated at reflux for sixteen hours, then cooled and concentrated in vacuo to a semi-solid oil. The oil is triturated with ethylacetate, filtered, and the filtrate washed with water, then dried (Na2SO4). Removal of the solvent gives the product as an oil (3.7 g.).

Aufarbeitung

  1. temperatureat reflux for sixteen hours
  2. temperaturecooled
  3. concentrationconcentrated in vacuo to a semi-solid oil
  4. customThe oil is triturated with ethylacetate
  5. filtrationfiltered
  6. washthe filtrate washed with water
  7. dry with materialdried (Na2SO4)
  8. customRemoval of the solvent

Quellen und Nachweise

ORD-Eintrag
ord-c21445e40754415299c7d97e6aa8a6ec
Quelldatensatz
uspto-grants-1978_05
Patentnummer
US04087552

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