HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Nicotinoyl chloride → 7-Nicotinoyloxy-2-{4-[bis-(4-fluorophenyl)methyl]piperazin-1-ylcarbonyl}-1,4-benzodioxin
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Nicotinoyl chloride | HCID 82604 | — |
| Edukt | 7-Hydroxy-2-{4-[bis(4-fluorophenyl)methyl]piperazin-1-ylcarbonyl}-1,4-benzodioxin | HCID 10994231 | — |
| Produkt | 7-Nicotinoyloxy-2-{4-[bis-(4-fluorophenyl)methyl]piperazin-1-ylcarbonyl}-1,4-benzodioxin | HCID 19392473 | 78% |
Reaktionsschritte
That compound is obtained in a yield of 78% starting from 7-hydroxy-2-{4-[bis-(4-fluorophenyl)methyl]piperazin-1-ylcarbonyl}-1,4-benzodioxin and nicotinoyl chloride by proceeding as for Example 53. ##STR76##
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05420132 |
| Quelldatensatz | uspto-grants-1995_05 |
| ORD ID | ord-0ed0f98eaa21458699b45544e350a72d |
| Quellennotiz | uspto-grants-1995_05 |