(+-)-2-Butanol → HCID 12783677, Verbindung
Reaktionsgleichung
[Na].Cl[C:3]1[NH:8][C:7](=[O:9])[C:6]([F:10])=[CH:5][N:4]=1.[CH:11]([OH:15])([CH2:13][CH3:14])[CH3:12]>>[CH:11]([O:15][C:3]1[NH:8][C:7](=[O:9])[C:6]([F:10])=[CH:5][N:4]=1)([CH2:13][CH3:14])[CH3:12]Komponenten
4
Versuchsvorschrift
A 300 ml quantity of absolute sec-butanol, 5.8 g of metal sodium and 14.9 g of 2-chloro-5-fluoropyrimidin-4-one are treated in the same manner as in Example 6 to obtain crystals, which are then recrystallized from a water-ethanol mixture to give 17.0 g of white crystalline 2-sec-butoxy-5-fluoropyrimidin-4-one in a yield of 91.4%, m.p. 104°-105° C.
Aufarbeitung
- customto obtain crystals, which
- customare then recrystallized from a water-ethanol mixture
Quellen und Nachweise
- ORD-Eintrag
- ord-ae6d5fe4d5744678bc8b9bfb8c08b3be
- Quelldatensatz
- uspto-grants-1978_05
- Patentnummer
- US04092313
Notizen zur Reaktion
Wird geladen…