HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Bromo-2-hydroxypyridine → 5-(Phenylthio)-2-pyridone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Bromo-2-hydroxypyridine | HCID 599528 | — |
| Edukt | benzenethiol, potassium salt | HCID 11789364 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Lösungsmittel | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Produkt | 5-(Phenylthio)-2-pyridone | HCID 20326562 | — |
Reaktionsschritte
A solution of 5-bromo-2-pyridone (17.3 g 0.1 mole) in N-methylpyrrolidinone (250 ml.) and potassium thiophenoxide (18.1 g, 0.12 mole) is heated at reflux for 12 hours under a nitrogen atmosphere. The reaction mixture is cooled and diluted with water. The product is collected by filtration, washed with water and dried to yeild 5-(phenylthio)-2-pyridone.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04092321 |
| Quelldatensatz | uspto-grants-1978_05 |
| ORD ID | ord-9ca0a3824ae444c9b4fee4d9894b9db9 |
| Quellennotiz | uspto-grants-1978_05 |