1,3-Dimethyl-5-ethoxycarbonylbarbituric acid → HCID 19811558, Verbindung

HRID 373105Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 373105
[F:1][C:2]([F:23])([O:9][CH:10]([F:22])[C:11]([F:21])([F:20])[O:12][C:13]1[CH:19]=[CH:18][C:16]([NH2:17])=[CH:15][CH:14]=1)[C:3]([F:8])([F:7])[CH:4]([F:6])[F:5].[CH3:24][N:25]1[C:32](=[O:33])[CH:31]([C:34](OCC)=[O:35])[C:29](=[O:30])[N:28]([CH3:39])[C:26]1=[O:27]>C1(C)C=CC=CC=1>[CH3:39][N:28]1[C:29](=[O:30])[CH:31]([C:34](=[O:35])[NH:17][C:16]2[CH:18]=[CH:19][C:13]([O:12][C:11]([F:21])([F:20])[CH:10]([O:9][C:2]([F:23])([F:1])[C:3]([F:7])([F:8])[CH:4]([F:5])[F:6])[F:22])=[CH:14][CH:15]=2)[C:32](=[O:33])[N:25]([CH3:24])[C:26]1=[O:27]

Komponenten

4

Edukt 2

HCID 5937141,3-Dimethyl-5-ethoxycarbonylbarbituric acidHCID 14819451HCID 14819451, Verbindung

Produkt 1

HCID 19811558HCID 19811558, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

14.50 g (40.6 mmol) of 4-(2-(1,1,2,2,3,3-hexafluoropropoxy)-1,1,2-trifluoroethoxy)-aniline were added to 9.26 g (40.6 mmol) of 1,3-dimethyl-5-ethoxycarbonylbarbituric acid in 100 ml of toluene, the mixture was stired under reflux for 2.5 hours and concentrated and the residue was recrystallized from methanol.

Aufarbeitung

  1. temperatureunder reflux for 2.5 hours
  2. concentrationconcentrated
  3. customthe residue was recrystallized from methanol

Quellen und Nachweise

ORD-Eintrag
ord-df7e9aa50fd54996b8f60d7cfc04b264
Quelldatensatz
uspto-grants-1992_11
Patentnummer
US05162327

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