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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 37331Erstellt: 23. Oktober 2026

2-Chlorothiophene → Methanone, (5-chloro-2-thienyl)phenyl-

https://huagongshe.com/de/reaction/37331

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-ChlorothiopheneHCID 7299—
Edukt4-tert-ButylphenolHCID 7393—
EduktBenzoyl chlorideHCID 7412—
ProduktMethanone, (5-chloro-2-thienyl)phenyl-HCID 901505—
Produkt2-Benzoyl-5-(4-t-butyl-phenoxy)thiopheneHCID 19935313—

Reaktionsschritte

2-benzoyl-5-chlorothiophene was synthesized via Friedel-Crafts acylation of benzoyl chloride with 2-chlorothiophene. This was reacted under standard conditions with 4-t-butyl phenol to produce 2-benzoyl-5-(4-t-butyl-phenoxy)thiophene. It was discovered by thin layer chromatography that the displacement of the acyl chlorine proceeds completely with no side reactions. Complete nucleophilic displacement demonstrates that this reaction meets the requirements necessary for high polymer formation via a step growth reaction.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05420224
Quelldatensatzuspto-grants-1995_05
ORD IDord-fefca5a18f9547ababd952357d410f7f
Quellennotizuspto-grants-1995_05