1-(2-Aminoethyl)-4-(2-methoxyphenyl)piperazine → (2S,4S)-N-{2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl}-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-(2-Aminoethyl)-4-(2-methoxyphenyl)piperazine	HCID 10399186	—
Edukt	(2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carbonyl chloride	HCID 57210646	—
Produkt	(2S,4S)-N-{2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl}-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide	HCID 57277562	—

Reaktionsschritte

This compound was prepared by the similar procedure as in the case of Example 8, excepting that 4-(2-aminoethyl)-1-(2-methoxyphenyl)pyperazine and (2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carbonyl chloride (Reference Example 1) were employed.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US05164391
Quelldatensatz	uspto-grants-1992_11
ORD ID	ord-db86b2de7c4f4826988bf977fda33a2a
Quellennotiz	uspto-grants-1992_11