Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Dimethylhydantoin | HCID 6491 | — |
| Edukt | Diphenyl Ether | HCID 7583 | — |
| Edukt | 5-Chloro-2-nitrobenzotrifluoride | HCID 67052 | — |
| Produkt | Nilutamide | HCID 4493 | — |
Reaktionsschritte
The following were introduced into 288 ml of phenyl oxide: 96.10 grams of 5,5-dimethyl-hydantoin, 170.86 grams of 2-nitro-5-chloro trifluoromethylbenzene and 89.40 grams of cupric oxide. The mixture was heated to 190° C. for about 23 hours, then cooled to 20° C. and filtered. The residue was characterized in the phenyl oxide filtrate by thin layer chromatography.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US05166358 |
|---|
| Quelldatensatz | uspto-grants-1992_11 |
|---|
| ORD ID | ord-250000bbc78844a9a114c6ed9b1ccd4b |
|---|
| Quellennotiz | uspto-grants-1992_11 |
|---|
