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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 374132Erstellt: 25. Oktober 2026

Neopentylamine → N-cyano N'-(2,2-dimethylpropyl)-2-pyridinecarboximidamide

https://huagongshe.com/reaction/374132

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktNeopentylamineHCID 79882—
Edukt2-Pyridinecarboximidic acid, N-cyano-, methyl esterHCID 10012189—
LösungsmittelMethanolHCID 887—
ProduktN-cyano N'-(2,2-dimethylpropyl)-2-pyridinecarboximidamideHCID 1973454394%

Reaktionsschritte

Methyl N-cyano-2-pyridinecarboximidate (0.50 g, 3.1 mmol) was dissolved in methanol (10 ml), 2,2-dimethylpropylamine (0.30 g, 3.4 mmol) was added, and the resulting mixture was stirred at room temperature for 30 minutes. After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was crystallized from dichloromethane-diethyl ether to give the title compound (0.63 g, 2.9 mmol, yield: 94%) as colorless needles.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05166347
Quelldatensatzuspto-grants-1992_11
ORD IDord-b23c20c0a12a4d68b8fa69d5b39b103a
Quellennotizuspto-grants-1992_11