Methanesulfonic Acid → 1-Methyl-2-isopropylamino-5-methoxycarbonylpyrimidinium sulfate

HRID 374429Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 374429
C[S:2]([OH:5])(=[O:4])=[O:3].[OH-].[CH3:7][N+:8]1[CH:13]=[C:12]([C:14]([O:16][CH3:17])=[O:15])[CH:11]=[N:10][C:9]=1[NH:18][CH:19]([CH3:21])[CH3:20]>O1CCCC1>[S:2]([O-:5])([O-:15])(=[O:4])=[O:3].[CH3:7][N+:8]1[CH:13]=[C:12]([C:14]([O:16][CH3:17])=[O:15])[CH:11]=[N:10][C:9]=1[NH:18][CH:19]([CH3:21])[CH3:20].[CH3:7][N+:8]1[CH:13]=[C:12]([C:14]([O:16][CH3:17])=[O:15])[CH:11]=[N:10][C:9]=1[NH:18][CH:19]([CH3:21])[CH3:20]

Komponenten

4

Edukt 2

HCID 6395Methanesulfonic AcidHCID 196988161-Methyl-2-isopropylamino-5-methoxycarbonylpyrimidinium hydroxide

Produkt 1

HCID 676602951-Methyl-2-isopropylamino-5-methoxycarbonylpyrimidinium sulfate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

1.09 mlg [sic] (16.78 mol; 1.61 g) of methanesulfonic acid is added to a solution of 1-methyl-2-isopropylamino-5-methoxycarbonylpyrimidinium hydroxide (3.48 g; 15.35 mol) dissolved in 100 ml of anhydrous tetrahydrofuran. The mixture is stirred under argon at room temperature for one hour. The precipitate which forms is filtered and then rinsed with ether.

Aufarbeitung

  1. filtrationThe precipitate which forms is filtered
  2. washrinsed with ether

Quellen und Nachweise

ORD-Eintrag
ord-c030ad34ab36425c8415fa7c69c341ec
Quelldatensatz
uspto-grants-1996_01
Patentnummer
US05480884

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