3-(2,3-Dihydro-1,4-benzodioxin-6-yl)acrylic acid → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethenyl)-1,3-dipropyl-, (E)-

Beteiligte Stoffe

Reaktionsschritte

Substantially the same procedure as in Reference Example 1 was repeated using 1.35 g (5.96 mmol) of 5,6-diamino-1,3-dipropyluracil and 1.35 g (6.55 mmol) of 3-(1,4-benzodioxan-6-yl)acrylic acid. Then, the resultant crude crystals were recrystallized from ethanol/water to give 1.54 g (yield 65%) of Compound 16 as white needles.

Herkunft & Nachweise