Methyl iodide → HCID 19935870, Verbindung
Reaktionsgleichung
[CH2:1]([O:3][C:4]([N:6]1[CH2:10][CH2:9][C:8]([OH:18])([C:11]2[CH:12]=[C:13]([S:16][CH3:17])[S:14][CH:15]=2)[CH2:7]1)=[O:5])[CH3:2].[CH3:19]I>>[CH2:1]([O:3][C:4]([N:6]1[CH2:10][CH2:9][C:8]([O:18][CH3:19])([C:11]2[CH:12]=[C:13]([S:16][CH3:17])[S:14][CH:15]=2)[CH2:7]1)=[O:5])[CH3:2]Komponenten
3
Versuchsvorschrift
Using an analogous procedure to that described in the second paragraph of the portion of Example 1 which is concerned with the preparation of starting materials, 1-ethoxycarbonyl-3-hydroxy-3-(2-methylthiothien-4-yl)pyrrolidine was reacted with methyl iodide to give 1-ethoxycarbonyl-3-methoxy-3-(2-methylthiothien-4-yl)pyrrolidine as an oil in 75% yield.
Quellen und Nachweise
- ORD-Eintrag
- ord-07b1ec3f841f4e3a95970065db1360f2
- Quelldatensatz
- uspto-grants-1995_05