Reaktionsgleichung
[C:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH:10]=[O:11])(=[O:3])[CH3:2].[Cl-].[CH3:13][NH2+]C.C=O>>[C:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][C:9](=[CH2:13])[CH:10]=[O:11])(=[O:3])[CH3:2]Komponenten
4
Versuchsvorschrift
16 g (101.1 mmol) of 6-acetoxyhexanal, 9.2 g (113 mmol) of dimethylammonium chloride and 9.2 ml (118.3 mmol) of a 37% solution of formaldehyde are stirred for 1 hour at a bath temperature of 110° C. The mixture is allowed to cool and extracted three times with CH2Cl2. The combined organic phases are dried over Na2SO4, filtered, and concentrated by evaporation giving 6-acetoxy-2-methylene-hexanal as a slightly yellowish oil which is further reacted without purification.
Aufarbeitung
- temperatureto cool
- extractionextracted three times with CH2Cl2
- dry with materialThe combined organic phases are dried over Na2SO4
- filtrationfiltered
- concentrationconcentrated by evaporation
Quellen und Nachweise
- ORD-Eintrag
- ord-201f78481e0b4b018808e9cfba22d1be
- Quelldatensatz
- uspto-grants-1996_01
- Patentnummer
- US05488140
Verknüpfte Notizen
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