Guanidine → N-(2-chloro-5-trifluoromethylbenzyl)-N-methylaminocarbonylguanidine hydrochloride
Reaktionsgleichung
[Cl:1][C:2]1C=[CH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[CH:7][C:3]=1CNC.C1N=[CH:18][N:17]([C:20]([N:22]2[CH:26]=[N:25][CH:24]=[CH:23]2)=[O:21])C=1.[NH2:27]C(N)=N>>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:7][C:8]([C:11]([F:12])([F:14])[F:13])=[CH:9][C:24]=1[CH2:23][N:22]([C:20]([NH:17][CH3:18])=[O:21])[C:26]([NH2:25])=[NH:27]Komponenten
4
Versuchsvorschrift
1.0 g of N-(2-chloro-5-trifluoromethylbenzyl)-N-methylamine was reacted with 0.75 g of CDI and 1.1 g of guanidine analogously to Example 23. 0.6 g of N-(2-chloro-5-trifluoromethylbenzyl)-N-methylaminocarbonylguanidine hydrochloride is obtained;