HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → 3-(4-nitrophenyl)-2-hydroxy-N-(2-aminoethyl)propionamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Nitric Acid | HCID 944 | — |
| Edukt | Atrolactic acid | HCID 1303 | — |
| Edukt | Ethylenediamine | HCID 3301 | — |
| Edukt | Methyl-p-nitrophenyl lactate | HCID 56998982 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Lösungsmittel | Sulfuric Acid | HCID 1118 | — |
| Produkt | 3-(4-nitrophenyl)-2-hydroxy-N-(2-aminoethyl)propionamide | HCID 19360733 | — |
Reaktionsschritte
Phenyl-lactic acid (available from Aldrich Chemical Co., Milwaukee, Wis.) is nitrated with nitric acid in sulfuric acid. P-nitrophenyl lactic acid is esterified with methanol and gaseous hydrochloric acid. Methyl-p-nitrophenyl lactate is condensed with ethylene diamine to provide the amide adduct, 3-(4-nitrophenyl)-2-hydroxy-N-(2-aminoethyl)propionamide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06022966 |
| Quelldatensatz | uspto-grants-2000_02 |
| ORD ID | ord-1457048d56e0407caf57f36a180c5d16 |
| Quellennotiz | uspto-grants-2000_02 |