Fluorobenzene → HCID 19360812, Verbindung

In the same apparatus and procedures as EXAMPLE 2 above, 18.8 ml (200 mmol) of fluorobenzene and 0.31 g (2.3 mmol) of aluminum chloride were alkylated with 5.61 g (22.8 mmol) of (2,3-dichloropropyl)trichlorosilane for 10 min at 70° C. The aluminum chloride catalyst was quenched with POCl3 and then stirred for another 1 hour to complete the deactivation. Freshly distilled hexane (50 ml) was added to the reaction mixture and insoluble solids in hexane were filtered from the organic soultion. After hexane and fluorobenzene were distilled, the reaction products were vacuum distilled to give 3.39 g of [3,3-bis(fluorophenyl)propyl]trichlorosilane (bp; 121-122° C./0.5 torr, yield; 41%) as a mixutre of isomers.

1. customThe aluminum chloride catalyst was quenched with POCl3
2. additionFreshly distilled hexane (50 ml) was added to the reaction mixture and insoluble solids in hexane
3. filtrationwere filtered from the organic soultion
4. distillationAfter hexane and fluorobenzene were distilled
5. distillationdistilled

ORD-Eintrag

ord-1388c80601624ea082e75cff451879fa

Quelldatensatz

uspto-grants-2000_02

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US06022987