HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diisopropylethylamine → trans-3,3-Diethoxy-1,2-cyclobutanedicarboxylic acid, diethyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diisopropylethylamine | HCID 81531 | — |
| Edukt | 1,1-Diethoxyethene | HCID 137673 | — |
| Edukt | Diethyl fumarate | HCID 638144 | — |
| Edukt | Diisobutyl aluminium chloride | HCID 16686353 | — |
| Produkt | trans-3,3-Diethoxy-1,2-cyclobutanedicarboxylic acid, diethyl ester | HCID 14378472 | — |
Reaktionsschritte
By the method of Example 1, diethyl fumarate was reacted at -40° C. with 2 equivalents of ketene diethyl acetal in the presence of 0.2 equivalents of ethyldiisopropylamine and 2 equivalents of diisobutylaluminium chloride. 1H NMR analysis of the reaction mixture showed that the yield was quantitative.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06025519 |
| Quelldatensatz | uspto-grants-2000_02 |
| ORD ID | ord-f3657800254e48c1868601930e701594 |
| Quellennotiz | uspto-grants-2000_02 |