HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Toluene → 8-(4-Benzyloxy-phenyl)-7-oxo-7H-thieno[2 3-a]quinolizine-10-carboxylic acid (2-hydroxy-ethyl)-phenyl-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Toluene | HCID 1140 | — |
| Edukt | Dimethylformamide | HCID 6228 | — |
| Edukt | alpha-(Aminomethyl)-3,4-dichlorobenzenemethanol | HCID 19349 | — |
| Edukt | Thionyl Chloride | HCID 24386 | — |
| Edukt | 8-[p-(benzyloxy)phenyl]-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid | HCID 19353629 | — |
| Lösungsmittel | Triethylamine | HCID 8471 | — |
| Produkt | 8-(4-Benzyloxy-phenyl)-7-oxo-7H-thieno[2 3-a]quinolizine-10-carboxylic acid (2-hydroxy-ethyl)-phenyl-amide | HCID 56628709 | — |
Reaktionsschritte
From 8-[p-(benzyloxy)phenyl]-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid with SOCl2 and DMF in toluene. Then treatment with triethylamine and phenylethanolamine in toluene.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06030984 |
| Quelldatensatz | uspto-grants-2000_02 |
| ORD ID | ord-310a4eb32bea45c7b495e07aa6d358c0 |
| Quellennotiz | uspto-grants-2000_02 |