1,3-Benzodioxole-5-carbonyl chloride → HCID 57467966, Verbindung

HRID 37931

Reaktionsgleichung

Reaktionsgleichung von HRID 37931
[CH2:1]([CH:3]1[NH:16][CH:15]=[C:14]([C:17]([O:19][CH2:20][CH3:21])=[O:18])[C:6]2[NH:7][C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][C:13]=3[C:5]=2[CH2:4]1)[CH3:2].[C:22](Cl)(=[O:32])[C:23]1[CH:31]=[CH:30][C:29]2[O:28][CH2:27][O:26][C:25]=2[CH:24]=1>>[CH2:1]([CH:3]1[N:16]([C:22](=[O:32])[C:23]2[CH:31]=[CH:30][C:29]3[O:28][CH2:27][O:26][C:25]=3[CH:24]=2)[CH:15]=[C:14]([C:17]([O:19][CH2:20][CH3:21])=[O:18])[C:6]2[NH:7][C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][C:13]=3[C:5]=2[CH2:4]1)[CH3:2]

Komponenten

3

Edukt 2

HCID 27347491,3-Benzodioxole-5-carbonyl chlorideHCID 66640163Ethyl 2-ethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate

Produkt 1

HCID 57467966HCID 57467966, Verbindung

Versuchsvorschrift

The title compound was prepared in a manner similar to that described in Example 2A by using ethyl 2-ethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate and piperonyloyl chloride. 1H-NMR (CDCl3): δ 10.38 (1H, br s), 8.15 (1H, s), 7.52 (1H, d), 7.37 (1H, d), 7.10 (4H, m), 6.88 (1H, d), 6.07 (1H, d), 6.06 (1H, d), 5.34 (1H, m), 4.16-4.33 (2H, m), 3.53 (1H, dd), 3.00 (1H, dd), 1.29-1.45 (2H, m), 1.24 (3H, t), 0.81 (3H, t); MS (ES): 433 (MH+).

Quellen und Nachweise

ORD-Eintrag
ord-f1cb350d574b4a86a8e31c0d46eeadeb
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08524704B2

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