HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethyl Sulfoxide → 2-Chloro-3-nitrobenzaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethyl Sulfoxide | HCID 679 | — |
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | 1-(Bromomethyl)-2-chloro-3-nitrobenzene | HCID 18363045 | — |
| Katalysator | Benzenesulfonic acid, 4-methyl-, silver(1+) salt (1:1) | HCID 85606 | — |
| Produkt | 2-Chloro-3-nitrobenzaldehyde | HCID 12667713 | 20% |
Reaktionsschritte
2-Chloro-3-nitrobenzaldehyde (150 mg, 20%) was prepared by reaction of 1-bromomethyl-2-chloro-3-nitrobenzene (1.0 g, 3.9 mmol) with silver p-toluenesulfonate (1.94 g, 1.75 equiv.) in DMSO in the presence of Et3N (4 mL, 7 equiv.) at rt for 1 hour.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06306870B1 |
| Quelldatensatz | uspto-grants-2001_10 |
| ORD ID | ord-01c384dd1916471a9090dc44208be730 |
| Quellennotiz | uspto-grants-2001_10 |