Methanol → Simvastatin

Beteiligte Stoffe

Reaktionsschritte

Alternatively, III may be agitated in a mixture of water and an organic solvent, preferably methanol, under high dilution conditions to produce simvastatin in its acid form. Simvastatin acid may be isolated by extraction or crystallization and relactonized to produce simvastatin.

Herkunft & Nachweise