HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Bromo-3-chloropropane → 1-(4-Chlorophenethyl)-4-(3-chloropropyl)piperazine dihydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Bromo-3-chloropropane | HCID 8006 | — |
| Edukt | Potassium Hydroxide | HCID 14797 | — |
| Edukt | 1-[2-(4-Chlorophenyl)ethyl]piperazine | HCID 12235714 | — |
| Lösungsmittel | Dimethyl Sulfoxide | HCID 679 | — |
| Produkt | 1-(4-Chlorophenethyl)-4-(3-chloropropyl)piperazine dihydrochloride | HCID 20153182 | 118,3% |
Reaktionsschritte
The procedure described in Example 17(a) was followed, using 6.5 g of 1-(4-chlorophenethyl)piperazine, 6.0 g of potassium hydroxide, 125 ml of dimethyl sulfoxide and 4.6 g of 1-bromo-3-chloropropane. Work-up, as described above, gave 6.4 g (59% of theory) of 1-(4-chlorophenethyl)-4-(3-chloropropyl)piperazine dihydrochloride as a white crystalline solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04722926 |
| Quelldatensatz | uspto-grants-1988_02 |
| ORD ID | ord-3718907b4bb04353b2d6e7ee3e40a47d |
| Quellennotiz | uspto-grants-1988_02 |