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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 382512Erstellt: 26. Oktober 2026

Hydrochloric Acid → (E)-1-(3-Methylpyrid-2-yl)-2-styryl-1H-benzimidazole hydrochloride

https://huagongshe.com/reaction/382512

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktHydrochloric AcidHCID 313—
Edukt2-Chloro-3-methylpyridineHCID 87603—
Edukt(E)-1-(2-pyridyl)-2-styryl-1H-benzimidazoleHCID 9796241—
LösungsmittelMethanolHCID 887—
Produkt(E)-1-(3-Methylpyrid-2-yl)-2-styryl-1H-benzimidazole hydrochlorideHCID 22736672—

Reaktionsschritte

Free base of the titled compound was prepared from 2-styryl-1-benzimidazole and 2-chloro-3-methylpyridine according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method B). The free base was treated with a 10% methanol solution of hydrogen chloride and concentrated to dryness. The residue was recrystallized from ethyl acetate/n-hexane to give the titled compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06310079B1
Quelldatensatzuspto-grants-2001_10
ORD IDord-c4cac8873b38476388b2519c8f40e940
Quellennotizuspto-grants-2001_10