HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Oxalic Acid → (E)-1-(2-Pyrimidyl)-2-styryl-1H-benzimidazole oxalate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Oxalic Acid | HCID 971 | — |
| Edukt | 2-Chloropyrimidine | HCID 74404 | — |
| Edukt | 2-(2-Phenylethenyl)-1h-benzimidazole | HCID 242965 | — |
| Edukt | (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole | HCID 9796241 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | (E)-1-(2-Pyrimidyl)-2-styryl-1H-benzimidazole oxalate | HCID 9930183 | — |
Reaktionsschritte
Free base of the titled compound was prepared from 2-styryl-1H-benzimidazole and 2-chloropyrimidine according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method B). The free base and oxalic acid were dissolved into ethyl acetate. Concentration and recrystallization from ethyl acetate/n-hexane yielded the titled compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06310079B1 |
| Quelldatensatz | uspto-grants-2001_10 |
| ORD ID | ord-d0e501acd8bd441a9a50c84f5696825d |
| Quellennotiz | uspto-grants-2001_10 |