Pyridine → 1,3,5-Triiodobenzene-2,4,6-trialdehyde

1,3,5-Triiodo-2,4,6-trihydroxymethylbenzene (4.5 g, 8.2 mmol) was dissolved in DMSO (80 ml). Triethylamine (51.7 ml, 371 mmol) and pyridine. SO3 (11.8 g, 74.2 mmol) were added and the mixture was stirred for two hours. The two phases were separated and the lower phase was cooled to 0° C., poured into water (150 ml) and stirred for 30 min at 0° C. The white solid was collected by filtration, washed with water and dried. Yield: 3.0 g (67%).

1. additionSO3 (11.8 g, 74.2 mmol) were added
2. customThe two phases were separated
3. additionpoured into water (150 ml)
4. stirringstirred for 30 min at 0° C
5. filtrationThe white solid was collected by filtration
6. washwashed with water
7. customdried

ORD-Eintrag

ord-f3dcd7a752cf42448ded2472fe4cb84b

Quelldatensatz

uspto-grants-2001_10

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US06310243B1