4-Nitro-2-(trifluoromethyl)anisole → 5-Amino-2-methoxybenzotrifluoride

Beteiligte Stoffe

Reaktionsschritte

1-Methoxy-4-nitro-2-trifluoromethyl-benzene (10 g, 45 mmol) was hydrogenated in a Paar apparatus with shaking at 50 psi for 4 hours, with 1 g 10 wt % Pd/C. The reaction mixture was filtered through celite, and the filtrate was evaporated in vacuo to give 8.6 g 4-Methoxy-3-trifluoromethyl-phenylamine, 99%, as a solid.

Herkunft & Nachweise