(5-Fluoropyridin-3-yl)boronic acid → Rac-[1-(3,4-dichloro-phenyl)-2-(5'-fluoro-[3,3']bipyridinyl-6-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(5-Fluoropyridin-3-yl)boronic acid	HCID 44717403	—
Edukt	Rac-[2-(5-bromo-pyridin-2-yl)-1-(3,4-dichloro-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester	HCID 68409891	—
Produkt	Rac-[1-(3,4-dichloro-phenyl)-2-(5'-fluoro-[3,3']bipyridinyl-6-yl)-2-oxo-ethyl]-carbamic acid tert-butyl ester	HCID 68410622	—

Reaktionsschritte

The title compound was prepared from rac-[2-(5-bromo-pyridin-2-yl)-1-(3,4-dichloro-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester and 5-fluoropyridine-3-boronic acid in analogy to Example 1b): MS (ISP): 476.1 and 478.1 (M+H)+.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08367838B2
Quelldatensatz	uspto-grants-2013_02
ORD ID	ord-38524549be2d4d7e8616dbbf1ae4f19a
Quellennotiz	uspto-grants-2013_02