HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(4-Bromo-2-methyl-phenyl)-5-fluoro-pyridine → Rac-[1-(3,4-dichloro-phenyl)-2-[4-(5-fluoro-pyridin-3-yl)-3-methyl-phenyl]-2-oxo-ethyl]-carbamic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(4-Bromo-2-methyl-phenyl)-5-fluoro-pyridine | HCID 68409948 | — |
| Edukt | Rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester | HCID 87442373 | — |
| Produkt | Rac-[1-(3,4-dichloro-phenyl)-2-[4-(5-fluoro-pyridin-3-yl)-3-methyl-phenyl]-2-oxo-ethyl]-carbamic acid tert-butyl ester | HCID 68408672 | — |
Reaktionsschritte
The title compound was prepared from rac-[(3,4-dichloro-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester (Intermediate 9) and 3-(4-bromo-2-methyl-phenyl)-5-fluoro-pyridine (Intermediate 12) in analogy to Example 1a): MS (ISP): 489.2 and 491.1 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08367838B2 |
| Quelldatensatz | uspto-grants-2013_02 |
| ORD ID | ord-66efa25ca539409cbe14d2d9df339209 |
| Quellennotiz | uspto-grants-2013_02 |