Cyclohexanol → Rac-[1-(4-chloro-phenyl)-2-(4-cyclohexyloxy-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester
Reaktionsgleichung
[C:1]([O:5][C:6](=[O:25])[NH:7][CH:8]([C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=1)[C:9]([C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1)=[O:10])([CH3:4])([CH3:3])[CH3:2].[CH:26]1(O)[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]1>>[C:1]([O:5][C:6](=[O:25])[NH:7][CH:8]([C:18]1[CH:19]=[CH:20][C:21]([Cl:24])=[CH:22][CH:23]=1)[C:9]([C:11]1[CH:16]=[CH:15][C:14]([O:17][CH:26]2[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]2)=[CH:13][CH:12]=1)=[O:10])([CH3:4])([CH3:2])[CH3:3]Komponenten
3
Versuchsvorschrift
The title compound was prepared from rac-[1-(4-chloro-phenyl)-2-(4-hydroxy-phenyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester and cyclohexanol in analogy to Example 9c): MS (ISN): 442.3 (M−H)−; MS (ISP): 444.2 (M+H)+, 344.1 ((M-Boc)+H)+ (100%).
Quellen und Nachweise
- ORD-Eintrag
- ord-7d49faf8ba3148b3b75fa89cf5bb8061
- Quelldatensatz