(4-Bromophenoxy)(tert-butyl)dimethylsilane → HCID 68410238, Verbindung

HRID 384951

Reaktionsgleichung

Reaktionsgleichung von HRID 384951
[C:1]([O:5][C:6](=[O:23])[NH:7][CH:8]([C:15]1[CH:20]=[CH:19][C:18]([CH3:21])=[C:17]([F:22])[CH:16]=1)[C:9](=[O:14])N(OC)C)([CH3:4])([CH3:3])[CH3:2].Br[C:25]1[CH:38]=[CH:37][C:28]([O:29][Si:30]([C:33]([CH3:36])([CH3:35])[CH3:34])([CH3:32])[CH3:31])=[CH:27][CH:26]=1>>[C:1]([O:5][C:6](=[O:23])[NH:7][CH:8]([C:15]1[CH:20]=[CH:19][C:18]([CH3:21])=[C:17]([F:22])[CH:16]=1)[C:9]([C:25]1[CH:38]=[CH:37][C:28]([O:29][Si:30]([C:33]([CH3:36])([CH3:35])[CH3:34])([CH3:31])[CH3:32])=[CH:27][CH:26]=1)=[O:14])([CH3:2])([CH3:3])[CH3:4]

Komponenten

3

Edukt 2

HCID 4227167(4-Bromophenoxy)(tert-butyl)dimethylsilaneHCID 87443461HCID 87443461, Verbindung2×

Produkt 1

HCID 68410238HCID 68410238, Verbindung

Versuchsvorschrift

The title compound was prepared from rac-[(3-fluoro-4-methyl-phenyl)-(methoxy-methyl-carbamoyl)-methyl]-carbamic acid tert-butyl ester (Intermediate 7) and (4-bromo-phenoxy)-tert-butyl-dimethyl-silane in analogy to Example 1a): MS (ISP): 358.3 ((M−Si(CH3)2C(CH3)3)+H)+ (100%).

Quellen und Nachweise

ORD-Eintrag
ord-28e5dc4d49fa402a900b91668c4a5962
Quelldatensatz
uspto-grants-2013_02
Patentnummer
US08367838B2

Verknüpfte Notizen

Wird geladen…