HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzenamine, 3-ethynyl- → Ethyl 4-[(3-ethynylphenyl)amino]-5,7-dihydro-6H-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidine-6-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzenamine, 3-ethynyl- | HCID 104682 | — |
| Edukt | Ethyl12-chloro-7-thia-4,9,11-triazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),9,11-tetraene-4-carboxylate | HCID 58116864 | — |
| Produkt | Ethyl 4-[(3-ethynylphenyl)amino]-5,7-dihydro-6H-pyrrolo[3',4':4,5]thieno[2,3-d]pyrimidine-6-carboxylate | HCID 58116910 | — |
Reaktionsschritte
In analogy to Example 22A, ethyl 4-chloro-5,7-dihydro-6H-pyrrolo[3′,4′:4,5]thieno[2,3-d]pyrimidine-6-carboxylate from Example 21A (235 mg, 0.83 mmol) and 3-ethynylaniline (102 mg, 0.87 mmol) were reacted to the title compound to yield 211 mg (67%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08524722B2 |
| Quelldatensatz | uspto-grants-2013_09 |
| ORD ID | ord-7d5a63bfe07342288577d481a66e9769 |
| Quellennotiz | uspto-grants-2013_09 |