2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 2-{[6-(5,6-Dihydroimidazo[1,2-a]pyrazin-7(8H)-ylcarbonyl)pyridin-2-yl]amino}-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide

Beteiligte Stoffe

Reaktionsschritte

The title compound was prepared as described in Example 1 using 2-bromo-6-{[(3R)-3-methoxypyrrolidin-1-yl]carbonyl}pyridine (200 mg, 0.65 mmol) and 2-amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (192 mg, 0.65 mmol) as starting materials.

Herkunft & Nachweise