1,1'-Carbonyldiimidazole → HCID 59526324, Verbindung

HRID 385966Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 385966
[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[C:4]([CH3:12])[N:3]=1.[C:13](N1C=CN=C1)(N1C=CN=C1)=[O:14]>CN(C)C=O.C(OCC)(=O)C>[Cl:1][C:2]1[N:3]=[C:4]([CH3:12])[C:5]([C:6]2[O:7][C:13](=[O:14])[NH:9][N:8]=2)=[CH:10][CH:11]=1

Komponenten

5

Edukt 2

HCID 682631,1'-CarbonyldiimidazoleHCID 595262086-Chloro-2-methylnicotinohydrazide

Produkt 1

HCID 59526324HCID 59526324, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 6228DimethylformamideLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

6-Chloro-2-methylnicotinohydrazide (60 mg, 0.32 mmol) and 1,1′-carbonylbis(1H-imidazole) (58 mg, 0.36 mmol) were taken up in dimethylformamide (1.6 ml). The reaction was heated overnight to 60° C. It was then allowed to cool to room temperature, taken up in ethyl acetate, and washed with water. The organic layer was concentrated under reduced pressure to afford the title compound.

Aufarbeitung

  1. temperatureThe reaction was heated overnight to 60° C
  2. washwashed with water
  3. concentrationThe organic layer was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-5fe1a4378f904037b7d8f81c20a2376a
Quelldatensatz
uspto-grants-2013_02
Patentnummer
US08367706B2

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