Benzyl 3-(4-hydroxyphenyl)propanoate → 3-(4-tert-Butoxycarbonylmethoxy-phenyl)-propionic acid benzyl ester

HRID 386718Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 386718
[CH2:1]([O:8][C:9](=[O:28])[CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH2:19][C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])=[C:14](Cl)[CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC(=O)CCC1C=CC(O)=CC=1)C1C=CC=CC=1>>[CH2:1]([O:8][C:9](=[O:28])[CH2:10][CH2:11][C:12]1[CH:13]=[CH:14][C:15]([O:18][CH2:19][C:20]([O:22][C:23]([CH3:25])([CH3:24])[CH3:26])=[O:21])=[CH:16][CH:17]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 14211262Benzyl 3-(4-hydroxyphenyl)propanoateHCID 667975133-(4-tert-Butoxycarbonylmethoxy-3-chloro-phenyl)-propionic acid benzyl ester

Produkt 1

HCID 667980173-(4-tert-Butoxycarbonylmethoxy-phenyl)-propionic acid benzyl ester

Versuchsvorschrift

This compound was prepared analogously to 3-(4-tert-butoxycarbonylmethoxy-3-chloro-phenyl)-propionic acid benzyl ester (Int. B step 2) by replacing 3-(3-chloro-4-hydroxy-phenyl)-propionic acid benzyl ester with 3-(4-hydroxy-phenyl)-propionic acid benzyl ester (commercially available).

Quellen und Nachweise

ORD-Eintrag
ord-d0bcf720817b4aec8b14ca46036a3699
Quelldatensatz
uspto-grants-2013_02
Patentnummer
US08372845B2

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