Hydrochloric Acid → Methyl 2-(3-bromo-4-methoxyphenyl)acetate

HRID 38701Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 38701
[Br:1][C:2]1[CH:3]=[C:4]([CH2:10][C:11]([OH:13])=[O:12])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].Cl.[CH3:15]O>>[CH3:15][O:12][C:11](=[O:13])[CH2:10][C:4]1[CH:5]=[CH:6][C:7]([O:8][CH3:9])=[C:2]([Br:1])[CH:3]=1

Komponenten

4

Edukt 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 1366153-Bromo-4-methoxyphenylacetic acid

Produkt 1

HCID 12717575Methyl 2-(3-bromo-4-methoxyphenyl)acetate

Versuchsvorschrift

To 3-bromo-4-methoxyphenylacetic acid (1.0 g, 4.1 mmol) in MeOH (20 mL) was added HCl (4N in 1,4-dioxane; 5 mL, 20 mmol), and the reaction was refluxed overnight. The mixture was concentrated to give the title compound.

Aufarbeitung

  1. temperaturethe reaction was refluxed overnight
  2. concentrationThe mixture was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-8270844e8c9c4a2aa36d4cea219762d2
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08524748B2

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