HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(2-Fluorophenyl)piperazine → HCID 25064648, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(2-Fluorophenyl)piperazine | HCID 70529 | — |
| Edukt | Diisopropylethylamine | HCID 81531 | — |
| Edukt | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Edukt | 3-(1-tert-butyl-5-(thiophene-2-yl)-1H-pyrazol-3-yl)propanal | HCID 86639925 | — |
| Produkt | HCID 25064648 | HCID 25064648 | — |
Reaktionsschritte
77 mg (73%) of target compound was obtained by using a method same as in Example 1 by using 3-(1-tert-butyl-5-(thiophene-2-yl)-1H-pyrazol-3-yl)propanal (50 mg, 0.191 mmol), 1-(2-fluorophenyl)piperazine (34 mg, 0.191 mmol), DIPEA (0.050 mL, 0.287 mmol) and NaBH(OAc)3 (121 mg, 0.573 mmol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08372844B2 |
| Quelldatensatz | uspto-grants-2013_02 |
| ORD ID | ord-5d38d8476fe944d294b67a57dd11a8c8 |
| Quellennotiz | uspto-grants-2013_02 |