HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(2,3-Xylyl)piperazine → 1-(2,3-dimethylphenyl)-4-(3-(1-phenyl-3-propyl-1H-pyrazol-5-yl)propyl)piperazine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(2,3-Xylyl)piperazine | HCID 70541 | — |
| Edukt | Diisopropylethylamine | HCID 81531 | — |
| Edukt | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Edukt | HCID 86639932 | HCID 86639932 | — |
| Produkt | 1-(2,3-dimethylphenyl)-4-(3-(1-phenyl-3-propyl-1H-pyrazol-5-yl)propyl)piperazine | HCID 68554245 | — |
Reaktionsschritte
146 mg (78%) of target compound was obtained by using a method same as in Example 1 by using 3-(1-phenyl-3-propyl-1H-pyrazol-5-yl)propanal (100 mg, 0.413 mmol), 1-(2,3-dimethylphenyl)piperazine (79 mg, 0.413 mmol), DIPEA (0.110 mL, 0.620 mmol) and NaBH(OAc)3 (263 mg, 1.239 mmol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08372844B2 |
| Quelldatensatz | uspto-grants-2013_02 |
| ORD ID | ord-7c739a4b97d84f3bba2f051cfcfd6502 |
| Quellennotiz | uspto-grants-2013_02 |