Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 38731Erstellt: 24. Oktober 2026

Hydrochloric Acid → HCID 178519917, Verbindung

https://huagongshe.com/de/reaction/38731

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktHydrochloric AcidHCID 313—
Edukttert-Butyl 4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylateHCID 7172298—
Lösungsmittel1,4-DioxaneHCID 31275—
ProduktHCID 178519917HCID 178519917—

Reaktionsbedingungen

Temperatur0 °C

Reaktionsschritte

To tert-butyl 4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylate (10 g) was added dropwise, at 0° C. a 4 molar solution of hydrogen chloride in 1,4-dioxane (100 ml). The reaction mixture was stirred at 0° C. and then gradually warmed to room temperature. After stirring overnight, the solvent and excess hydrogen chloride were removed. This gave 4-(4-formyl-1,3-thiazol-2-yl)piperidinium chloride (9 g).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08524743B2
Quelldatensatzuspto-grants-2013_09
ORD IDord-7edf2078af034c5e8e68ff894daec008
Quellennotizuspto-grants-2013_09