Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070, Verbindung

HRID 389051Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 389051
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

Komponenten

3

Edukt 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

Produkt 1

HCID 21925070HCID 21925070, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 313Hydrochloric AcidLösungsmittel

Versuchsvorschrift

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6N HCl (20 mL). After 20 h, the reaction mixture was concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in the next reaction.

Aufarbeitung

  1. concentrationthe reaction mixture was concentrated to dryness
  2. customthe residue was dried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-2775abbed9244b129ae3cb81da301a7e
Quelldatensatz
uspto-grants-2013_02
Patentnummer
US08378099B2

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