3-Methylacetophenone → 2-Bromo-1-(3-methylphenyl)ethan-1-one

Beteiligte Stoffe

Reaktionsschritte

To a solution of 1-(3-methylphenyl)ethanone (2 g) in ethyl ether (20 mL) is added bromine (726 μL) at 0° C. The mixture is treated with an aqueous solution of sodium bicarbonate, extracted with ethyl ether, dried over magnesium sulfate, concentrated and purified on silica gel (ethyl acetate/cyclohexane 0/100) to give the desired compound.

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