Trifluoroacetic acid → HCID 44623930, Verbindung
Reaktionsgleichung
[CH3:1][N:2]([CH2:10][C:11]([NH:13][CH2:14][CH2:15][CH2:16][NH:17][C:18]1[N:19]=[C:20]([NH:29][C:30]2[CH:35]=[CH:34][CH:33]=[C:32]([CH3:36])[CH:31]=2)[C:21]2[C:27](=[O:28])[NH:26][CH:25]=[CH:24][C:22]=2[N:23]=1)=[O:12])C(=O)OC(C)(C)C.C(O)(C(F)(F)F)=O>ClCCl>[CH3:1][NH:2][CH2:10][C:11]([NH:13][CH2:14][CH2:15][CH2:16][NH:17][C:18]1[N:19]=[C:20]([NH:29][C:30]2[CH:35]=[CH:34][CH:33]=[C:32]([CH3:36])[CH:31]=2)[C:21]2[C:27](=[O:28])[NH:26][CH:25]=[CH:24][C:22]=2[N:23]=1)=[O:12]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of 1,1-dimethylethyl methyl(2-{[3-({4[(3-methylphenyl)amino]-5-oxo-5,6-dihydropyrido[4,3-d]pyrimidin-2-yl}amino)propyl]amino}-2-oxoethyl)carbamate (30 mg, 0.061 mmol) in Dichloromethane (DCM) (1 mL) was added TFA (0.5 mL, 6.49 mmol), and the reaction mixture was stirred for 1.5 h. It was concentrated and the residue was further dried under high vacuum to give 30 mg of pure product.