Acetyl chloride → Chloromethyl 2,4-dichlorophenyl ether

HRID 390788

Reaktionsgleichung

Reaktionsgleichung von HRID 390788
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[O:9][CH2:10]S(C)=O.C([Cl:17])(=O)C>C(Cl)Cl>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[O:9][CH2:10][Cl:17]

Komponenten

4

Edukt 2

HCID 6367Acetyl chlorideHCID 685778492,4-Dichloro-1-methanesulfinylmethoxy-benzene

Produkt 1

HCID 12353529Chloromethyl 2,4-dichlorophenyl etherAusbeute 98,9 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

To an ice-water cooled solution of 2,4-dichloro-1-methanesulfinylmethoxy-benzene (8 g, 33.46 mmol) in DCM (100 mL) was added dropwise a solution of acetylchloride (2.6 mL, 36.80 mmol) in DCM (10 mL). The reaction mixture was allowed to reach room temperature during 2 hrs at which time the volatiles were evaporated in vacuo affording ˜7 g of crude 2,4-dichloro-1-chloromethoxy-benzene which was used without further purification.

Aufarbeitung

  1. customthe volatiles were evaporated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-8a4b4157fc4e4b759f68fbb32b016ff6
Quelldatensatz
uspto-grants-2013_02
Patentnummer
US08383683B2

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