HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(4-Aminophenyl)-1-propanol → (2e,4e,6e,8e)-3,7-Dimethyl-n-(pyridin-4-yl)-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(4-Aminophenyl)-1-propanol | HCID 235875 | — |
| Edukt | Retinoic Acid | HCID 444795 | — |
| Edukt | Edc hobt | HCID 86583742 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | (2e,4e,6e,8e)-3,7-Dimethyl-n-(pyridin-4-yl)-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenamide | HCID 59539418 | — |
Reaktionsschritte
Coupling of (4-amino)phenylpropanol (453 mg; 3 mmol) and retinoic acid (600 mg, 2 mmol) in anhydrous DMF (4 mL) using standard EDC/HOBt coupling condtions yielded the desired amide as a pale, yellow solid (600 mg, 69%). EMS m/z: 434 ([M+1]+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08383836B2 |
| Quelldatensatz | uspto-grants-2013_02 |
| ORD ID | ord-a39325d79a5a4919aba96709be717534 |
| Quellennotiz | uspto-grants-2013_02 |