HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(4-Iodophenyl)ethan-1-one → (s)-5-[(4-Acetylphenyl)ethynyl]-n-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(4-Iodophenyl)ethan-1-one | HCID 72869 | — |
| Edukt | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| Produkt | (s)-5-[(4-Acetylphenyl)ethynyl]-n-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953842 | 86% |
Reaktionsschritte
In a manner similar to that describe in Example 434 a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 4-iodoacetophenone were reacted to give the title compound as a light yellow foam (52 mg, 86%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08383825B2 |
| Quelldatensatz | uspto-grants-2013_02 |
| ORD ID | ord-81b5eb7fe2d143c6900463b22a74d1ce |
| Quellennotiz | uspto-grants-2013_02 |