Methyl iodide → 1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide
Reaktionsgleichung
[CH2:1]([N:3]1[CH2:8][CH2:7][C:6](=[O:9])[CH2:5][CH2:4]1)[CH3:2].[CH3:10][I:11]>CC(C)=O>[I-:11].[CH2:1]([N+:3]1([CH3:10])[CH2:8][CH2:7][C:6](=[O:9])[CH2:5][CH2:4]1)[CH3:2]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A solution of 100 g (0.789 mol) of 1-ethyl-4-oxopiperidine in 1000 mL of acetone was stirred at rt in a water bath. To this was added 62.2 mL (142 g, 1 mol) of methyl iodide, dropwise at such a rate to keep the temperature below 30 degrees. A precipitate developed within minutes and the mixture was stirred at rt for 4 h. The mixture was filtered and the precipitate washed with acetone and dried to afford the title compound as a white solid. Mass spectrum (ESI) 142 (M+).
Aufarbeitung
- customthe temperature below 30 degrees
- waitA precipitate developed within minutes
- filtrationThe mixture was filtered
- washthe precipitate washed with acetone
- customdried
Quellen und Nachweise
- ORD-Eintrag
- ord-87a7885c7a4544d6b1fd2241658e57ce
- Quelldatensatz
- uspto-grants-2004_10
- Patentnummer
- US06809199B2
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