HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl heptanoate → 2-[(4-Benzyloxy-2-methyl-phenyl)-hydroxy-methyl]-heptanoic acid methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl heptanoate | HCID 7826 | — |
| Edukt | Lithium diisopropylamide | HCID 2724682 | — |
| Edukt | 2-Methyl 4-benzyloxybenzaldehyde | HCID 2759806 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 2-[(4-Benzyloxy-2-methyl-phenyl)-hydroxy-methyl]-heptanoic acid methyl ester | HCID 68616679 | — |
Reaktionsschritte
In analogy to the procedure described in example 125 a], methyl heptanoate was deprotonated with lithium diisopropylamide and reacted with 4-benzyloxy-2-methyl-benzaldehyde in tetrahydrofuran to obtain 2-[(4-benzyloxy-2-methyl-phenyl)-hydroxy-methyl]-heptanoic acid methyl ester as a mixture of two diastereomeric racemates as light yellow oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06809110B2 |
| Quelldatensatz | uspto-grants-2004_10 |
| ORD ID | ord-c3eee6e3a1914b60be869ec077ced694 |
| Quellennotiz | uspto-grants-2004_10 |