2,5-Dimethoxybenzaldehyde → 2,5-Dimethoxy-4'-prop-2-enyloxychalcone

HRID 394969Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 394969
[CH3:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][CH:12]=[CH2:13])=[CH:6][CH:5]=1)=[O:3].[CH3:14][O:15][C:16]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][C:17]=1[CH:18]=O>>[CH3:14][O:15][C:16]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][C:17]=1[CH:18]=[CH:1][C:2]([C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][CH:12]=[CH2:13])=[CH:6][CH:5]=1)=[O:3]

Komponenten

3

Edukt 2

HCID 667262,5-DimethoxybenzaldehydeHCID 959691-(4-(2-Propen-1-yloxy)phenyl)ethanone

Produkt 1

HCID 541484062,5-Dimethoxy-4'-prop-2-enyloxychalconeAusbeute 83 %

Versuchsvorschrift

1.76 g (10 mmol) of 4-allyloxyacetophenone and 1.66 g (10 mmol) of 2,5-dimethoxy-benzaldehyde were under an inert atmosphere (argon) dissolved in 10 ml of dry freshly distilled ethanol, and 100 mg of sodium hydroxide was added to the solution. The mixture was left under stirring for 2.5 h and filtered. The precipitate was recrystallized from methanol to give 2.50 g (83%) of 2,5-dimethoxy-4′-prop-2-enyloxychalcone, m.p. 86-87° C.

Aufarbeitung

  1. dissolutiondissolved in 10 ml
  2. dry with materialof dry freshly distilled ethanol, and 100 mg of sodium hydroxide
  3. additionwas added to the solution
  4. waitThe mixture was left
  5. filtrationfiltered
  6. customThe precipitate was recrystallized from methanol

Quellen und Nachweise

ORD-Eintrag
ord-c1cd1a4b4781411cbfa4335d7cded9f1
Quelldatensatz
uspto-grants-2003_08
Patentnummer
US06603046B1

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